Welcome to nDesign™ Gateway
nDesign Gateway enables the selection of fixed-content nCounter Gene Expression Panels and the assembly of custom Gene Expression CodeSets.
Designing a custom CodeSet with nDesign Gateway
Select Chemistry: NanoString offers two types of chemistry for custom CodeSets. nCounter Standard chemistry is NanoString’s original chemistry in which the biotin label and molecular barcode are covalently attached to the target specific probe. nCounter Elements are General Purpose Reagents (GPRs) in which the biotin label and molecular barcode are hybridized to target-specific probes (sold separately) via unique tags. nCounter Elements GPRs enable researchers to build their own custom CodeSets by combining Elements GPRs with probes procured from an oligonucleotide vendor. nCounter Elements GPRs offer the option of an Extension CodeSet which can be combined with an existing core CodeSet in order to include additional targets.
Select Alternate Probes: By default, nDesign Gateway will assign an optimal probe for each gene that you select. Optimal probes meet the NanoString standard design criteria and are recommended unless you want to measure a specific exon or region. If you would like to select an alternate probe you can do so by clicking the + to expand the row for the gene of interest. The gene viewer will display the available probes.
Getting a quote through nDesign Gateway
Once a panel is selected or a custom CodeSet design is complete, the order can be submitted for a quote by clicking the button in the lower right corner of the CodeSet view. You will receive an email confirming your quote submission and a NanoString sales representative will follow up with you promptly.
Frequently Asked Questions
- What if I don't see my favorite gene on the list?
- Do you have probes for other species?
- How many probes per target do you recommend?
- How do I match NanoString probe sequences with other manufacturer’s probe sequences?
- Can I use this site to design my CNV or custom miRNA assays?
- I would like to target a different exon/region of my target than I see listed here or I am interested in isoform specific probes. How do I do this?
- How do I select all probes that were returned from my search?
- I already have a list of genes selected in Excel or other format, how do I submit this to NanoString? Do I have to search for each gene and add it to my CodeSet?
- Why can’t I find the PAM50 panel in nDesign Gateway?